SCHEMBL6676547

SCHEMBL6676547

NC(=S)N/N=C/c1ncccc1O

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RRM2 P31350 4/20 0.73
RRM1 P23921 1/20 0.73
RRM2B Q7LG56 1/20 0.73
CISD1 Q9NZ45 1/20 0.73
NCOA3 Q9Y6Q9 3/20 0.68
NCOA1 Q15788 2/20 0.68
KDM4E B2RXH2 3/20 0.58
GAA P10253 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
LMNA P02545 1/20 0.55
MAPT P10636 1/20 0.55
MPI P34949 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CTH P32929 2/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6676551 1.00 RRM2 (0.73) RRM2RRM1RRM2BCISD1NCOA3
Triapine SCHEMBL29365763 0.84 RRM2 (1.00) RRM2RRM1RRM2BCISD1NCOA3
Triapine SCHEMBL29370 0.84 RRM2 (1.00) RRM2RRM1RRM2BCISD1NCOA3
Triapine SCHEMBL29362841 0.84 RRM2 (1.00) RRM2RRM1RRM2BCISD1NCOA3
Triapine SCHEMBL31238438 0.84 RRM2 (1.00) RRM2RRM1RRM2BCISD1NCOA3
Triapine SCHEMBL29371 0.84 RRM2 (1.00) RRM2RRM1RRM2BCISD1NCOA3
SCHEMBL9289701 0.84 RRM2 (0.52) RRM2RRM1RRM2BCISD1NCOA3
SCHEMBL9267384 0.84 RRM2 (0.52) RRM2RRM1RRM2BCISD1NCOA3
SCHEMBL1904117 0.77 RRM2 (0.70) RRM2RRM1RRM2BCISD1NCOA3
SCHEMBL8684404 0.76 RRM2 (0.57) RRM2RRM1RRM2BCISD1NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1006 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
EP-4729047-A1 COSMETIC COMPOSITION COMPRISING BIODEGRADABLE POLYMER PARTICLES CJ Cheiljedang Corporation (KR) 2026-04-22 EP claimed
EP-4729079-A1 IMPLANT COMPRISING BIODEGRADABLE POLYMER, MANUFACTURING METHOD THEREFOR, AND COMPOSITION THEREFOR CJ Cheiljedang Corporation (KR) 2026-04-22 EP claimed
EP-4722374-A1 METHOD FOR PRODUCING 3-HYDROXYPROPIONIC ACID LG Chem, Ltd. (KR) 2026-04-08 EP claimed
EP-4714429-A1 BIODEGRADABLE SCRUB PARTICLES AND SKIN CLEANSING COMPOSITION COMPRISING SAME CJ Cheiljedang Corporation (KR) 2026-03-25 EP claimed
US-20260043033-A1 MICROORGANISM SIMULTANEOUSLY PRODUCING 1,3-PROPANEDIOL AND 3-HYDROXYPROPIONIC ACID, AND USE THEREOF LG CHEM, LTD. (KR) 2026-02-12 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
US-20260009055-A1 METHOD FOR PREPARING PURIFIED POLYHYDROXYALKANOATE CJ CHEILJEDANG CORPORATION (KR) 2026-01-08 US claimed
US-20250382454-A1 BIODEGRADABLE FILM HAVING HIGH BARRIER PROPERTIES AND LOW NOISE LEVEL, AND BIODEGRADABLE RESIN COMPOSITION FOR SAME Microworks Co., Ltd. (KR) 2025-12-18 US claimed
US-12486212-B2 Production and separation of 3-hydroxypropionic acid NOROO IC CO., LTD. (US) 2025-12-02 US claimed
WO-2022170191-A1 RECOMBINANT MICROORGANISMS AND USES THEREFOR LANZATECH, INC. (US) 2022-08-11 WO claimed
US-11377671-B2 Co-production pathway for 3-HPA and acetyl-CoA derivatives from malonate semialdehyde BRASKEM S.A. (BR) 2022-07-05 US claimed
US-11359057-B2 Block copolymer LG CHEM, LTD. (KR) 2022-06-14 US claimed
WO-2022098162-A1 METHOD FOR PRODUCING 3-HYDROXYPROPIONIC ACID 주식회사 엘지화학 2022-05-12 WO claimed
CN-114317388-A Construction method of pseudomonas denitrificans lacking malonate semialdehyde bypass metabolic pathway 江苏师范大学 2022-04-12 CN claimed
CN-108291231-B Promoter system for inducible expression of 3-hydroxypropionic acid and method for biologically producing 3-hydroxypropionic acid using the same 纳路IC有限公司 2022-04-08 CN claimed
CN-107828671-B Compositions and methods for producing 3-hydroxypropionic acid 卡吉尔公司 2022-03-08 CN claimed
US-20220064654-A1 COMPOSITIONS AND METHODS FOR 3-HYDROXYPROPIONIC ACID PRODUCTION CARGILL, INCORPORATED (US) 2022-03-03 US claimed
WO-2022025710-A1 METHOD FOR PREPARING 3-HYDROXYPROPIONIC ACID THROUGH TWO STEPS 주식회사 엘지화학 2022-02-03 WO claimed
WO-2022019949-A1 ENZYMES AND METHODS FOR PRODUCTION OF MALONIC ACID AND DERIVATIVES THEREOF CARGILL, INCORPORATED (US) 2022-01-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC3, HDAC1, HDAC4 RRM2 275/4885RRM1 507/4885RRM2B 209/4885
US-20260009055-A1 METHOD FOR PREPARING PURIFIED POLYHYDROXYALKANOATE FTO, PHB1, HAO2 RRM2 3333/4885RRM1 2595/4885RRM2B 2904/4885
US-12486212-B2 Production and separation of 3-hydroxypropionic acid GRHPR, HPD, HAAO RRM2 3374/4885RRM1 3287/4885RRM2B 3666/4885
US-20260043033-A1 MICROORGANISM SIMULTANEOUSLY PRODUCING 1,3-PROPANEDIOL AND 3-HYDROXYPROPIONIC ACID, AND USE THEREOF PGD, HPD, PHGDH RRM2 2494/4885RRM1 3469/4885RRM2B 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.