Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | RRM2 | P31350 | 3/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19668661 | 0.83 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MMP2CHRM1TSHR | |
| SCHEMBL16712006 | 0.82 | FGF23 (0.45) | ALDH1A1L3MBTL1MMP2CHRM1TSHR | |
| SCHEMBL29402625 | 0.82 | FGF23 (0.45) | ALDH1A1L3MBTL1MMP2CHRM1TSHR | |
| SCHEMBL19003507 | 0.80 | NPC1 (0.40) | ALDH1A1L3MBTL1MMP2CHRM1TSHR | |
| SCHEMBL25515518 | 0.76 | NFE2L2 (0.49) | — | |
| SCHEMBL8599677 | 0.76 | SRC (0.43) | ALDH1A1L3MBTL1MMP2CHRM1TSHR | |
| SCHEMBL6676551 | 0.74 | RRM2 (0.73) | L3MBTL1RRM2RRM1RRM2BCISD1 | |
| SCHEMBL6676547 | 0.74 | RRM2 (0.73) | L3MBTL1RRM2RRM1RRM2BCISD1 | |
| SCHEMBL9289701 | 0.74 | RRM2 (0.52) | L3MBTL1RRM2RRM1RRM2BCISD1 | |
| SCHEMBL9267384 | 0.74 | RRM2 (0.52) | L3MBTL1RRM2RRM1RRM2BCISD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |