Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9271591 | 0.85 | AR (0.38) | KDM4EALDH1A1 | |
| SCHEMBL5812554 | 0.84 | CTSS (0.34) | — | |
| SCHEMBL5812558 | 0.82 | RXFP1 (0.36) | KDM4EGLAALDH1A1 | |
| SCHEMBL5812533 | 0.82 | ADORA1 (0.33) | KDM4EGLAALDH1A1 | |
| SCHEMBL5819964 | 0.79 | MAOA (0.34) | KDM4EGLAALDH1A1 | |
| SCHEMBL5819960 | 0.79 | KIF11 (0.35) | ALDH1A1 | |
| SCHEMBL5818900 | 0.78 | — | — | |
| SCHEMBL9269860 | 0.77 | KDM4E (0.32) | KDM4E | |
| SCHEMBL9015141 | 0.74 | RXFP1 (0.35) | KDM4EGLAALDH1A1 | |
| SCHEMBL9390222 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018122-A2 | HETEROARYLPYRROLES | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |