Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976497 | 0.87 | MMP2 (0.47) | GRM6MMP2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL9269299 | 0.77 | SMN1; SMN2 (0.36) | GRM6MMP2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2730411 | 0.75 | GRM6 (0.49) | GRM6MMP2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27651123 | 0.74 | GRM6 (0.42) | GRM6MMP2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL6577861 | 0.74 | ALOX15 (0.43) | GRM6KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3869825 | 0.72 | GRM6 (0.33) | GRM6KDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL6995362 | 0.72 | ALDH1A1 (0.53) | GRM6KDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL6112152 | 0.72 | GRM6 (0.48) | GRM6KDM4EALDH1A1HSD17B10GLA | |
| SCHEMBL7393739 | 0.72 | POLB (0.52) | THRBMEN1KMT2APARP1POLB | |
| SCHEMBL30142643 | 0.71 | KMT2A (0.38) | GAAMAPTKMT2ASMN1; SMN2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243929-B1 | Polypeptide and protein derivatives and process for their preparation | OFFORD ROBIN EWART (CH) | 1995-09-27 | — | — | EP | disclosed |