Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582763 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDNAMPTKMT2A | |
| SCHEMBL4582716 | 0.74 | MGLL (0.48) | — | |
| SCHEMBL20147826 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKMT2AHSD17B10 | |
| SCHEMBL7378563 | 0.69 | SYK (0.57) | MAPTKMT2AMEN1SYKHSD17B10 | |
| SCHEMBL13350424 | 0.69 | GAA (0.55) | ALDH1A1MAPTHPGDNAMPTKDM4E | |
| SCHEMBL19349021 | 0.68 | NAMPT (0.58) | ALDH1A1HPGDNAMPTKMT2AGAA | |
| SCHEMBL799425 | 0.68 | NAMPT (0.58) | ALDH1A1HPGDNAMPTKMT2AGAA | |
| SCHEMBL9078752 | 0.66 | NNMT (0.42) | ALDH1A1HPGDNNMTNAMPTKMT2A | |
| SCHEMBL20147821 | 0.66 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL6182061 | 0.64 | CTSS (0.54) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995027705-A1 | AROMATIC AMIDE COMPOUNDS AND METAL CHELATES THEREOF | BRACCO INTERNATIONAL B.V. (NL) | 1995-10-19 | — | — | WO | disclosed |