Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274915 | 0.83 | LMNA (0.53) | LMNASMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9268482 | 0.80 | PPARG (0.42) | PPARGPPARAALOX5PTGESTDP1 | |
| SCHEMBL10860502 | 0.80 | AR (0.47) | LMNASMN1; SMN2KMT2AKDM4ETDP1 | |
| SCHEMBL10789684 | 0.79 | LTA4H (0.44) | SMN1; SMN2KMT2ANPC1RAB9APPARG | |
| SCHEMBL23295252 | 0.78 | NQO1 (0.34) | LMNASMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9856170 | 0.77 | CA12 (0.44) | LMNASMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9856294 | 0.77 | PPARG (0.39) | SMN1; SMN2PPARGPPARAALOX5PTGES | |
| SCHEMBL9856269 | 0.77 | TAAR1 (0.44) | SMN1; SMN2PPARGPPARAALOX5PTGES | |
| SCHEMBL10789677 | 0.77 | PPARG (0.33) | LMNASMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL9268024 | 0.77 | NR1I2 (0.49) | LMNASMN1; SMN2KMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389651-A | Nitrogen-containing heterocyclyl-oxy and -thio compounds useful as pesticides | SANDOZ LTD. (CH) | 1995-02-14 | — | — | US | disclosed |