Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816423 | 0.91 | CNR2 (0.52) | CNR2PLA2G4BPRKCALMNACNR1 | |
| SCHEMBL13933052 | 0.84 | DGKA (0.53) | CNR2PLA2G4BTP53TSHR | |
| SCHEMBL13933053 | 0.84 | DGKA (0.53) | CNR2PLA2G4BTP53TSHR | |
| SCHEMBL13933056 | 0.80 | TSHR (0.59) | CNR2PLA2G4BMAPTALDH1A1LMNA | |
| SCHEMBL19062107 | 0.77 | CNR1 (0.65) | CNR2PRKCAMAPTALDH1A1CNR1 | |
| SCHEMBL3176361 | 0.77 | CNR1 (0.65) | CNR2PRKCAMAPTALDH1A1CNR1 | |
| SCHEMBL3937050 | 0.77 | LMNA (0.70) | PRKCAMAPTALDH1A1LMNAPRKCE | |
| SCHEMBL6338116 | 0.76 | CHRNB2 (0.50) | MAPTTP53TSHR | |
| SCHEMBL16012189 | 0.75 | ALDH1A1 (0.56) | PRKCAMAPTALDH1A1LMNATSHR | |
| SCHEMBL6378043 | 0.75 | BRD4 (0.52) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436170-A | Crosslinking | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1995-07-25 | — | — | US | disclosed |