Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247213 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BTMPRSS15PRSS1NQO2 | |
| SCHEMBL9259191 | 0.89 | NQO2 (0.38) | ITGB3ITGA2BNPC1F2NQO2 | |
| SCHEMBL9250808 | 0.88 | ITGB3 (0.36) | ITGB3ITGA2BTMPRSS15NPC1F2 | |
| SCHEMBL9257112 | 0.87 | TLR8 (0.36) | ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL9251260 | 0.85 | F10 (0.36) | F2F10PRSS1POLB | |
| SCHEMBL9568422 | 0.85 | F2 (0.37) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL9250591 | 0.82 | MIF (0.43) | ITGB3ITGA2BTMPRSS15NPC1F2 | |
| SCHEMBL8863938 | 0.82 | TMPRSS15 (0.36) | ITGB3ITGA2BTMPRSS15NPC1F2 | |
| SCHEMBL9251916 | 0.80 | TMPRSS15 (0.36) | ITGB3ITGA2BTMPRSS15NPC1F2 | |
| SCHEMBL9250788 | 0.79 | ALDH1A1 (0.34) | ITGB3ITGA2BTMPRSS15F10NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |