Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | F7 | P08709 | 3/20 | 0.34 |
| ▸ | F3 | P13726 | 3/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250761 | 0.90 | F2 (0.40) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL9259191 | 0.87 | NQO2 (0.38) | F2F7F3ITGB3ITGA2B | |
| SCHEMBL9257112 | 0.86 | TLR8 (0.36) | ITGB3ITGA2BMAPT | |
| SCHEMBL9280389 | 0.85 | ITGB3 (0.35) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL9250808 | 0.82 | ITGB3 (0.36) | F2F7ITGB3ITGA2BF10 | |
| SCHEMBL9251260 | 0.80 | F10 (0.36) | F2F7F3F10PRSS1 | |
| SCHEMBL9250591 | 0.79 | MIF (0.43) | F2ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL9248487 | 0.78 | AGER (0.38) | ITGB3ITGA2BALDH1A1MAPTMEN1 | |
| SCHEMBL9250788 | 0.77 | ALDH1A1 (0.34) | ITGB3ITGA2BF10NQO2ALDH1A1 | |
| SCHEMBL9257188 | 0.77 | NQO2 (0.38) | F2ITGB3ITGA2BF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |