Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL6374630 | 0.95 | TSHR (0.80) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Sulfuric Acid SCHEMBL6374621 | 0.91 | TSHR (0.80) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Sulfuric Acid SCHEMBL28079923 | 0.91 | TSHR (0.80) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Ammonia Solution, Strong SCHEMBL11066251 | 0.89 | TSHR (0.70) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrochloric Acid SCHEMBL11436653 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrochloric Acid SCHEMBL11436657 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Hydrochloric Acid SCHEMBL548983 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Ammonia Solution, Strong SCHEMBL61101 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Ammonia Solution, Strong SCHEMBL11066280 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA | |
| Ammonia Solution, Strong SCHEMBL4472414 | 0.88 | TSHR (0.94) | TSHRSMN1; SMN2CYP2D6POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643555-A1 | A METHOD OF PRODUCING HERBICIDAL GRANULAR PRODUCTS | Hoechst Schering AgrEvo GmbH (DE) | 1995-03-22 | — | — | EP | disclosed |
| WO-1993005652-A1 | A METHOD OF PRODUCING HERBICIDAL GRANULAR PRODUCTS | KEMIRA AGRO OY (FI) | 1993-04-01 | — | — | WO | disclosed |