Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ARNT | P27540 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939311 | 0.79 | KMT2A (0.45) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL14941196 | 0.74 | LDHA (0.41) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL9281258 | 0.72 | L3MBTL1 (0.51) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL9275026 | 0.69 | MAPT (0.37) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL9279745 | 0.69 | KDM4E (0.45) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL6956189 | 0.69 | TDP1 (0.53) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL6956134 | 0.69 | TDP1 (0.53) | KMT2AMEN1MAPTALDH1A1TDP1 | |
| SCHEMBL9274355 | 0.68 | MEN1 (0.41) | KMT2AMEN1MAPTTDP1L3MBTL1 | |
| SCHEMBL28410859 | 0.68 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL9278847 | 0.68 | KDM4E (0.52) | KMT2AMEN1MAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411040-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | President and Fellows of Harvard College (US) | 2018-12-12 | — | — | EP | disclosed |
| WO-2017136480-A1 | SMALL MOLECULES FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-10 | — | — | WO | disclosed |
| EP-2646107-A2 | AGENT DELIVERY SYSTEMS FOR SELECTIVE NEUROMODULATION | Spinal Modulation Inc. (US) | 2013-10-09 | — | — | EP | disclosed |
| WO-2012174537-A2 | SMALL MOLECULE SCREENING FOR MOUSE SATELLITE CELL PROLIFERATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012075337-A2 | DIRECTED DELIVERY OF AGENTS TO NEURAL ANATOMY | SPINAL MODULATION, INC. (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012050884-A2 | CARDIAC GLYCOSIDES ARE POTENT INHIBITORS OF INTERFERON-BETA GENE EXPRESSION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-04-19 | — | — | WO | disclosed |