Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769996 | 0.82 | PTGS2 (0.50) | PTGS2MAOBMAOAPTGS1MEN1 | |
| SCHEMBL299826 | 0.76 | ELANE (0.42) | MEN1KMT2A | |
| SCHEMBL9769995 | 0.75 | PTGS2 (0.46) | PTGS2MAOBMAOAPTGS1MEN1 | |
| SCHEMBL9147599 | 0.75 | PTGS2 (0.44) | PTGS2MAOBMAOAPTGS1MEN1 | |
| SCHEMBL8627211 | 0.75 | KMT2A (0.49) | KMT2AMAPTHTT | |
| SCHEMBL9773217 | 0.74 | PTGS2 (0.43) | PTGS2MAOBMAOAPTGS1MEN1 | |
| SCHEMBL7339889 | 0.74 | HSPB1 (0.43) | PTGS2MEN1KMT2ANPC1MAPT | |
| SCHEMBL9655691 | 0.74 | PTGS2 (0.46) | PTGS2MAOBPTGS1MEN1KMT2A | |
| SCHEMBL9133114 | 0.73 | PTGS2 (0.56) | PTGS2MAOBMEN1KMT2ANPC1 | |
| SCHEMBL10333121 | 0.72 | HTT (0.57) | PTGS2MAOBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5400172-A | Multi-layer optical elements formed from free standing films and method of making same | HOECHST CELANESE CORP. (US) | 1995-03-21 | — | — | US | disclosed |