Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769995 | 0.82 | PTGS2 (0.46) | PTGS2PTGS1MAOBMAOAKMT2A | |
| SCHEMBL9283142 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1MAOBMAOAKMT2A | |
| SCHEMBL10079590 | 0.79 | CA12 (0.49) | KMT2AMEN1LMNAMAPTHTT | |
| SCHEMBL29047967 | 0.77 | PTGS2 (0.46) | PTGS2PTGS1MAOBMAOAKMT2A | |
| SCHEMBL9480422 | 0.76 | PTGS2 (0.57) | PTGS2MAOBKMT2AMEN1LMNA | |
| SCHEMBL9480426 | 0.76 | PTGS2 (0.57) | PTGS2MAOBKMT2AMEN1LMNA | |
| SCHEMBL7564773 | 0.76 | ELANE (0.41) | KMT2AMAPTHTTTDP1 | |
| SCHEMBL9147599 | 0.76 | PTGS2 (0.44) | PTGS2PTGS1MAOBMAOAKMT2A | |
| SCHEMBL28411012 | 0.75 | ALDH1A3 (0.53) | KMT2AMEN1LMNAMAPT | |
| SCHEMBL9773217 | 0.75 | PTGS2 (0.43) | PTGS2PTGS1MAOBMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5044725-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-09-03 | — | — | US | disclosed |
| US-5002361-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4936644-A | Polarization-insensitive interferometric waveguide electrooptic modulator | HOECHST CELANESE CORP. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4932738-A | Polarization-insensitive interferometric waveguide electrooptic modulator | HOECHST CELANESE CORP. (US) | 1990-06-12 | — | — | US | disclosed |