Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769996 | 0.82 | PTGS2 (0.50) | PTGS2MAOBMEN1KMT2ANPC1 | |
| SCHEMBL9283142 | 0.75 | PTGS2 (0.49) | PTGS2MAOBMEN1KMT2ANPC1 | |
| SCHEMBL11967011 | 0.75 | L3MBTL1 (0.41) | TP53LMNARAB9ANPSR1MAPT | |
| SCHEMBL9655691 | 0.74 | PTGS2 (0.46) | PTGS2MAOBMEN1KMT2ANPC1 | |
| SCHEMBL9480426 | 0.74 | PTGS2 (0.57) | PTGS2KDM4ETP53MAOBMEN1 | |
| SCHEMBL9480422 | 0.74 | PTGS2 (0.57) | PTGS2KDM4ETP53MAOBMEN1 | |
| SCHEMBL10598448 | 0.74 | MGLL (0.52) | PTGS2MGLLMEN1KMT2ANPC1 | |
| SCHEMBL11967010 | 0.74 | GAA (0.42) | TP53LMNARAB9ANPSR1MAPT | |
| SCHEMBL11967008 | 0.74 | GAA (0.42) | TP53LMNARAB9ANPSR1MAPT | |
| SCHEMBL28678913 | 0.74 | POLB (0.48) | TP53KMT2AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5044725-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-09-03 | — | — | US | disclosed |
| US-5002361-A | Polymeric thin film waveguide media | HOECHST CELANESE CORP. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4971416-A | Polymeric waveguide device for phase matched second harmonic generation | HOECHST CELANESE CORP. (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0368042-A2 | Frequency doubling polymeric waveguide | HOECHST CELANESE CORPORATION (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4865406-A | SUPPORTED POLYMERIC THIN FILM EXHIBITING SECOND ORDER NONLINEA R OPTICAL RESPONSE | HOECHST CELANESE CORP. (US) | 1989-09-12 | — | — | US | disclosed |