SCHEMBL9285

SCHEMBL9285

OB(O)c1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 1.00
CA2 P00918 4/20 1.00
ENPP2 Q13822 3/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA14 Q9ULX7 1/20 0.59
CA5B Q9Y2D0 1/20 0.59
LTA4H P09960 5/20 0.57
TSHR P16473 1/20 0.57
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MGLL Q99685 1/20 0.56
MAOA P21397 1/20 0.50
PARP10 Q53GL7 1/20 0.47
SRD5A2 P31213 1/20 0.45
FFAR1 O14842 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Magnesium Chloride Anhydrous SCHEMBL20694917 0.92 CA1 (0.84) CA1CA2ENPP2CA4CA6
SCHEMBL6001606 0.90 CA2 (0.81) CA1CA2ENPP2CA4CA6
SCHEMBL16151490 0.86 CA1 (0.75) CA1CA2LTA4HTSHRNR1H2
SCHEMBL8437226 0.84 CA1 (0.71) CA1CA2ENPP2CA4CA6
SCHEMBL10269840 0.84 CA1 (0.72) CA1CA2ENPP2CA4CA6
SCHEMBL3787238 0.82 CA1 (0.69) CA1CA2ENPP2CA4CA6
Diphenylether SCHEMBL787081 0.82 LTA4H (0.75) CA1CA2LTA4HTSHRNR1H2
SCHEMBL14165789 0.81 ENPP2 (0.71) CA1CA2ENPP2LTA4HNR1H2
SCHEMBL31563612 0.80 CA1 (0.67) CA1CA2ENPP2CA4CA6
SCHEMBL257834 0.80 CA1 (0.67) CA1CA2ENPP2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-20250101021-A1 METHODS OF MAKING TOLEBRUTINIB PRINCIPIA BIOPHARMA INC. (US) 2025-03-27 US claimed
CN-119390717-A Preparation method of 4-phenoxyphenylboronic acid 安徽英特美科技有限公司 2025-02-07 CN claimed
CN-119384411-A Method for preparing tolmetinib 普林斯匹亚生物制药公司 2025-01-28 CN claimed
CN-118344321-A Gamma-pyrone derivative and synthetic method and application thereof 武汉轻工大学 2024-07-16 CN claimed
CN-118255693-A Biphenyl compound and application thereof in preparation of medicines for treating leukemia, lung cancer and breast cancer 大连理工大学 2024-06-28 CN claimed
CN-115572297-B Pyrazolopyrimidine-containing o-phenylenediamine derivative, and preparation method and application thereof 山东大学 2024-04-26 CN claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
WO-2023244587-A1 METHODS OF MAKING TOLEBRUTINIB GENZYME CORPORATION (US) 2023-12-21 WO claimed
WO-2017017619-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB AND NEW SYNTHESIS INTERMEDIATE OLON S.P.A. (IT) 2017-02-02 WO claimed
WO-2016132383-A1 PROCESS FOR THE PREPARATION OF IBRUTINIB MYLAN LABORATORIES LIMITED (IN) 2016-08-25 WO claimed
US-9340575-B2 Agonists and antagonists of the urotensinergic system INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2016-05-17 US claimed
EP-2729184-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM Institut National de la Recherche Scientifique (CA) 2014-05-14 EP claimed
US-20140113872-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2014-04-24 US claimed
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
WO-2012149644-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2012-11-08 WO claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140113872-A1 NOVEL AGONISTS AND ANTAGONISTS OF THE UROTENSINERGIC SYSTEM UTS2R, SCTR, PLAUR CA1 4204/4885CA2 3993/4885ENPP2 205/4885
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy GFER, MUC1, CTH CA1 1918/4885CA2 2856/4885ENPP2 854/4885
US-20250101021-A1 METHODS OF MAKING TOLEBRUTINIB ABL1, JAK2, JAK1 CA1 4884/4885CA2 4757/4885ENPP2 3782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.