Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.63 |
| ▸ | FABP3 | P05413 | 1/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465739 | 0.86 | MAPT (0.54) | HNF4AMAPTHDAC8ALDH1A1ALOX15 | |
| SCHEMBL7079586 | 0.85 | BCAT2 (0.69) | HNF4AFABP3FABP4FABP5MAPT | |
| SCHEMBL3069640 | 0.84 | FOLH1 (0.50) | HNF4AFABP3FABP4FABP5MAPT | |
| SCHEMBL7407371 | 0.83 | HNF4A (0.73) | HNF4AFABP3FABP4FABP5MAPT | |
| Methane SCHEMBL28640150 | 0.82 | ALDH1A1 (0.53) | HNF4AMAPTBCAT2ALDH1A1SMN1; SMN2 | |
| Benzene SCHEMBL28480917 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| Benzene SCHEMBL1403559 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL133057 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL26624744 | 0.81 | HNF4A (0.69) | HNF4AFABP3FABP4FABP5BCAT2 | |
| SCHEMBL2162181 | 0.80 | MAPT (0.61) | HNF4AMAPTHDAC8ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107129458-B | Carbazole oxime ester compound and synthesis method and application thereof | 江苏和成新材料有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-106278967-B | Acyl oxime ester compound for UV curing material and synthetic method and application thereof | 江苏和成新材料有限公司 | 2020-08-07 | — | — | CN | disclosed |
| US-5434264-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
| US-5300642-A | α, α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532054-A1 | Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |