SCHEMBL9290282

SCHEMBL9290282

CC(C)(C)c1ccc2c3c(cccc13)C(=O)N2CC(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RORC P51449 2/20 0.48
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
APAF1 O14727 1/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
BRD4 O60885 14/20 0.44
MEN1 O00255 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14707343 0.85 ALDH1A1 (0.66) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL9290317 0.81 CYP1B1 (0.56) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL9290283 0.81 NPSR1 (0.52) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL9290277 0.80 KEAP1 (0.55) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL9290284 0.80 ALDH1A1 (0.47) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL9290384 0.79 MAPT (0.45) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL12561339 0.79 BRD4 (0.47) ALDH1A1MAPTSMN1; SMN2KDM4EAPAF1
SCHEMBL12601548 0.77 PKM (0.58) ALDH1A1SMN1; SMN2KDM4EBRD4PKM
SCHEMBL9290310 0.77 ALDH1A1 (0.45) RORCALDH1A1MAPTSMN1; SMN2KDM4E
SCHEMBL12561275 0.77 RORC (0.44) RORCALDH1A1MAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 RORC 1641/4885ALDH1A1 776/4885MAPT 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.