SCHEMBL9290283

SCHEMBL9290283

CC(C)(C)c1ccc2c3c(cccc13)C(=O)N2Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.52
MAPT P10636 4/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
CYP1B1 Q16678 1/20 0.52
RGS12 O14924 1/20 0.52
USP2 O75604 1/20 0.52
RECQL P46063 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.50
RORC P51449 1/20 0.50
ALDH1A1 P00352 5/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
APAF1 O14727 1/20 0.47
GAA P10253 1/20 0.47
THRB P10828 1/20 0.47
ALDH2 P05091 1/20 0.47
CHRM1 P11229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14707343 0.84 ALDH1A1 (0.66) NPSR1MAPTMEN1KMT2AL3MBTL1
SCHEMBL9720960 0.81 L3MBTL1 (0.70) NPSR1MAPTMEN1KMT2ALMNA
SCHEMBL9290282 0.81 RORC (0.48) NPSR1MAPTMEN1KMT2AL3MBTL1
SCHEMBL9290377 0.80 CYP1B1 (0.59) NPSR1MAPTMEN1KMT2ALMNA
SCHEMBL9290284 0.79 ALDH1A1 (0.47) NPSR1MAPTMEN1KMT2AL3MBTL1
SCHEMBL9290277 0.79 KEAP1 (0.55) NPSR1MAPTMEN1KMT2AL3MBTL1
SCHEMBL12561203 0.79 ALDH1A1 (0.67) NPSR1MAPTMEN1KMT2ALMNA
SCHEMBL23563379 0.78 KMT2A (0.64) NPSR1MAPTMEN1KMT2ALMNA
SCHEMBL9290437 0.78 KMT2A (0.56) NPSR1MAPTMEN1KMT2ALMNA
SCHEMBL12561342 0.78 MAPT (0.53) NPSR1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 NPSR1 42/4885MAPT 4299/4885MEN1 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.