Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28472302 | 0.81 | SIGMAR1 (0.57) | CYP1A2CYP2D6TAAR1SLC18A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL29264265 | 0.80 | SIGMAR1 (0.55) | CYP1A2CYP2D6TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL9404672 | 0.79 | SIGMAR1 (0.47) | TRPA1MAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL16356133 | 0.75 | TRPA1 (0.52) | TRPA1MAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL8976958 | 0.75 | TAAR1 (0.63) | TRPA1CYP2D6TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL178552 | 0.75 | TAAR1 (0.63) | TRPA1CYP2D6TAAR1SLC18A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL23524437 | 0.73 | TAAR1 (0.61) | TRPA1CYP2D6TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL4680337 | 0.72 | SIGMAR1 (0.66) | TRPA1MAOAMAOBCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL10560323 | 0.70 | SIGMAR1 (0.63) | TRPA1MAOAMAOBCYP1A2CYP2D6 | |
| SCHEMBL29432962 | 0.70 | TRPA1 (0.47) | TRPA1CYP2D6SIGMAR1SLC6A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6087798-A | — | — | None | — | — | JP | disclosed |
| JP-H0687798-A | PREPARATION OF NEW PHENYL PROPYNYL AMINE DERIVATIVE | CHINOIN GYOGYSZER V T G RT | 1994-03-29 | — | — | JP | disclosed |
| US-4925878-A | N-PHENYLISOPROPYL-N-METHYL-PROPYLVINYLAMINES; ORAL ADMINISTRATION | CHINOIN GYOGYSZER- ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-05-15 | — | — | US | disclosed |
| EP-0294441-A1 | COMPOSITION TO PREVENT SEASICKNESS. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1988-12-14 | — | — | EP | disclosed |
| WO-1988004552-A1 | COMPOSITION TO PREVENT SEASICKNESS | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1988-06-30 | — | — | WO | disclosed |