Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680337 | 0.79 | SIGMAR1 (0.66) | SIGMAR1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL9290755 | 0.79 | TRPA1 (0.44) | SIGMAR1CYP1A2CYP2D6SLC6A4TRPA1 | |
| SCHEMBL29432962 | 0.78 | TRPA1 (0.47) | SIGMAR1CYP3A4CYP2D6TSHRSLC6A4 | |
| Hydrochloric Acid SCHEMBL10560323 | 0.78 | SIGMAR1 (0.63) | SIGMAR1CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL25918452 | 0.76 | SIGMAR1 (0.68) | SIGMAR1SLC6A4TRPA1 | |
| SCHEMBL21034838 | 0.75 | SIGMAR1 (0.59) | SIGMAR1CYP1A2CYP2D6SLC6A4TRPA1 | |
| SCHEMBL178552 | 0.75 | TAAR1 (0.63) | SIGMAR1CYP2D6SLC6A4TRPA1 | |
| SCHEMBL8976958 | 0.75 | TAAR1 (0.63) | SIGMAR1CYP2D6SLC6A4TRPA1 | |
| SCHEMBL16356133 | 0.75 | TRPA1 (0.52) | SIGMAR1CYP1A2CYP2D6SLC6A4TRPA1 | |
| SCHEMBL22431530 | 0.74 | SIGMAR1 (0.70) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6128152-A | — | — | None | — | — | JP | disclosed |
| JP-H06128152-A | PERCUTANEOUS COMPOSITION | CHINOIN GYOGYSZER V T G RT | 1994-05-10 | — | — | JP | disclosed |