Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | CALCR | P30988 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291070 | 1.00 | APLNR (0.54) | APLNRNMUR2NMUR1F2MC4R | |
| SCHEMBL30272525 | 0.91 | F2 (0.56) | NMUR2NMUR1F2MC4RREN | |
| SCHEMBL30272526 | 0.90 | F2 (0.58) | NMUR2NMUR1F2MC4RREN | |
| SCHEMBL29878778 | 0.90 | F2 (0.55) | APLNRNMUR2NMUR1F2MC4R | |
| SCHEMBL29390515 | 0.86 | OPRM1 (0.52) | F2RENOPRM1OPRD1OPRK1 | |
| SCHEMBL6516908 | 0.86 | REN (0.58) | RENOPRM1OPRD1OPRK1 | |
| SCHEMBL29525618 | 0.86 | REN (0.58) | RENOPRM1OPRD1OPRK1 | |
| SCHEMBL30422302 | 0.86 | F2 (0.53) | APLNRNMUR2NMUR1F2REN | |
| SCHEMBL31384593 | 0.85 | OPRK1 (0.56) | RENOPRK1 | |
| SCHEMBL30272450 | 0.83 | F2 (0.46) | NMUR2F2MC4RCALCROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5367064-A | α-1-antichymotrypsin, analogues and methods of production | THE TRUSTEES OF THE UNIVERSITY OF PENNYLSVANIA (US) | 1994-11-22 | — | — | US | disclosed |
| US-5252725-A | α-1-antichymotrypsin, analogues and methods of production | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1993-10-12 | — | — | US | disclosed |
| US-5079336-A | α-1-antichymotrypsin, analogues and methods of production | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1992-01-07 | — | — | US | disclosed |