Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.40 |
| ▸ | LDHB | P07195 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FHIT | P49789 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713707 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL9097000 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL267943 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8201854 | 0.73 | FHIT (0.49) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL28298632 | 0.73 | MAPT (0.42) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL23827472 | 0.71 | FHIT (0.44) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL14989236 | 0.70 | LDHA (0.48) | LDHALDHBRECQLPTPN1PTPN11 | |
| SCHEMBL22418967 | 0.70 | LDHA (0.48) | LDHALDHBRECQLPTPN1PTPN11 | |
| SCHEMBL10714467 | 0.69 | KDM4E (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL23827438 | 0.69 | MAPT (0.41) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284847-A | Neurological and psychological disorders; antagonist at the glycine binding site on the N-methyl-D-aspartate receptor complex | NOVO NORDISK A/S (DK) | 1994-02-08 | — | — | US | disclosed |