SCHEMBL929326

SCHEMBL929326

CN(C(=O)c1cc(Cl)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl)C1CC1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.38
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
MALT1 Q9UDY8 13/20 0.35
PSD A5PKW4 1/20 0.33
NTRK1 P04629 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533122 0.90 DHODH (0.37) DHODHTSHRMALT1PSD
SCHEMBL17998607 0.88 DHODH (0.37) DHODHMALT1PSD
SCHEMBL589853 0.88 DHODH (0.41) DHODHHPGDTSHRMALT1
SCHEMBL28454560 0.85 HPGD (0.36) DHODHHPGDTSHRMALT1
SCHEMBL28517966 0.84 DHODH (0.41) DHODHMALT1PSDNTRK1
SCHEMBL28867330 0.84 DHODH (0.41) DHODHMALT1PSDNTRK1
SCHEMBL28867333 0.84 DHODH (0.41) DHODHMALT1PSD
SCHEMBL10028783 0.84 DHODH (0.41) DHODHMALT1PSDNTRK1
SCHEMBL31060006 0.83 DHODH (0.40) DHODHMALT1PSDNTRK1
SCHEMBL29416636 0.83 IDO1 (0.38) DHODHMALT1PSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2306831-B1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA (JP) 2018-03-28 EP claimed
US-8946297-B2 Solid composition for pest control ISHIHARA SANGYO KAISHA, LTD. (JP) 2015-02-03 US claimed
US-8529926-B2 Pesticidal compositions ISHIHARA SANGYO KAISHA, LTD. (JP) 2013-09-10 US claimed
US-20110130427-A1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-02 US claimed
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-01-20 US claimed
US-20100317700-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA LTD. (JP) 2010-12-16 US claimed
EP-2255625-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-01 EP claimed
EP-0509864-B1 Stabilized compositions of halogenated polymers containing a compound of lead or organo tin RHONE POULENC CHIMIE (FR) 1997-06-25 EP claimed
EP-0509864-A1 Stabilized compositions of halogenated polymers containing a compound of lead or organo tin RHONE-POULENC CHIMIE (FR) 1992-10-21 EP claimed
US-10299475-B2 Pesticide ISHIHARA SANGYO KAISHA, LTD. (JP) 2019-05-28 US disclosed
US-20180360032-A1 ADDITIVE PACKAGE COMPOSITIONS FOR PESTICIDE SUSPENSION CONCENTRATE FORMULATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2018-12-20 US disclosed
EP-2306831-B1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA (JP) 2018-03-28 EP disclosed
US-9688634-B2 Pest control agent ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-06-27 US disclosed
US-9629360-B2 Water-based pesticidal suspension ISHIHARA SANGYO KAISHA, LTD. (JP) 2017-04-25 US disclosed
EP-0895524-A1 STABILIZATION OF HALOGENATED POLYMERS WITH RESPECT TO LIGHT, AND STABILIZING COMPOSITIONS RHODIA CHIMIE (FR) 1999-02-10 EP disclosed
WO-1998055542-A1 COMPOSITION BASED ON CALCIUM OF MAGNESIUM ACETYLACETONATE AND FREE OR CHELATED β-DIKETONES, PREPARATION AND USE RHODIA CHIMIE (FR) 1998-12-10 WO disclosed
WO-1998055440-A1 COATED CALCIUM OR MAGNESIUM ACETYLACETONATE, AND ITS USE FOR STABILISING HALOGENATED POLYMERS RHODIA CHIMIE (FR) 1998-12-10 WO disclosed
WO-1997040094-A1 STABILIZATION OF HALOGENATED POLYMERS WITH RESPECT TO LIGHT, AND STABILIZING COMPOSITIONS RHODIA CHIMIE (FR) 1997-10-30 WO disclosed
EP-0509864-B1 Stabilized compositions of halogenated polymers containing a compound of lead or organo tin RHONE POULENC CHIMIE (FR) 1997-06-25 EP disclosed
EP-0509864-A1 Stabilized compositions of halogenated polymers containing a compound of lead or organo tin RHONE-POULENC CHIMIE (FR) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360032-A1 ADDITIVE PACKAGE COMPOSITIONS FOR PESTICIDE SUSPENSION CONCENTRATE FORMULATIONS SLC16A7, MPC2, PKD2 DHODH 1374/4885HPGD 3516/4885TSHR 3158/4885
US-20100317700-A1 PESTICIDAL COMPOSITIONS ACHE, AAAS, AADAC DHODH 1328/4885HPGD 3206/4885TSHR 3035/4885
US-10299475-B2 Pesticide DDT, ACHE, KCNH1 DHODH 3136/4885HPGD 4335/4885TSHR 279/4885
US-20110130427-A1 PESTICIDAL COMPOSITION PHOSPHO1, NAAA, NAPEPLD DHODH 2539/4885HPGD 4199/4885TSHR 2996/4885
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ANTXR2, STOM, SARAF DHODH 4143/4885HPGD 4699/4885TSHR 2077/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.