Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 2/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156247 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1SMORAB9APAX8 | |
| SCHEMBL12003383 | 0.78 | KDM4E (0.42) | KDM4EALDH1A1SMOPAX8CCNB2 | |
| SCHEMBL11260109 | 0.71 | FFAR4 (0.47) | KDM4EALDH1A1RAB9AFFAR4NPC1 | |
| SCHEMBL12098558 | 0.70 | KDM5A (0.43) | KDM4EALDH1A1SMOPAX8FFAR4 | |
| SCHEMBL16857579 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1SMORAB9ACCNB2 | |
| SCHEMBL6341120 | 0.69 | KDM4E (0.47) | KDM4EALDH1A1RAB9APOLBNPC1 | |
| SCHEMBL5221752 | 0.68 | ALOX15 (0.52) | KDM4EALDH1A1RAB9AHMGCRFFAR4 | |
| SCHEMBL6341439 | 0.68 | KDM4E (0.48) | KDM4EALDH1A1RAB9AFFAR4POLB | |
| SCHEMBL15609847 | 0.67 | SMN1; SMN2 (0.40) | KDM4EALDH1A1RAB9ASLC11A2POLB | |
| SCHEMBL11248894 | 0.67 | ALDH1A1 (0.54) | KDM4EALDH1A1RAB9AFFAR4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292744-A | 1-[pyri(mi)dyl-(2)]-5-hydroxy-pyrazole microbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| US-5175176-A | Used for protection of industrial materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-29 | — | — | US | disclosed |