Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 2/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321477 | 0.85 | CASP1 (0.46) | MEN1KMT2ACASP1CTSD | |
| SCHEMBL7322873 | 0.83 | CES1 (0.35) | ALOX5CES1KDM4AKDM5AKDM4C | |
| SCHEMBL7329312 | 0.80 | CTSD (0.42) | MEN1KMT2ACASP1CTSD | |
| SCHEMBL7327018 | 0.78 | CASP1 (0.47) | ALOX5CASP1CTSD | |
| SCHEMBL9296303 | 0.77 | ANPEP (0.41) | ANPEPCTSD | |
| SCHEMBL7322631 | 0.77 | CASP1 (0.34) | CASP1 | |
| SCHEMBL7332144 | 0.77 | CASP1 (0.34) | CASP1 | |
| SCHEMBL7332732 | 0.77 | CASP1 (0.34) | CASP1 | |
| SCHEMBL7329315 | 0.76 | ALOX5 (0.37) | KMT2AALOX5CES1KDM4AKDM5A | |
| SCHEMBL27286594 | 0.76 | ANPEP (0.43) | MEN1KMT2AALOX5ANPEPKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594586-A4 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 1994-08-17 | — | — | EP | disclosed |
| EP-0594586-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1991010442-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-25 | — | — | WO | disclosed |