Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 6/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321477 | 0.95 | CASP1 (0.46) | CTSDCASP1HPGDMEN1KMT2A | |
| SCHEMBL7322813 | 0.88 | CTSD (0.37) | CTSDCASP1 | |
| SCHEMBL7319638 | 0.87 | CTSK (0.46) | CTSDCASP1 | |
| SCHEMBL7327018 | 0.87 | CASP1 (0.47) | CTSDCASP1HPGDSMN1; SMN2 | |
| SCHEMBL9296228 | 0.84 | CASP1 (0.54) | CTSDCASP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7332099 | 0.84 | LNPEP (0.37) | CTSDCASP1HPGDSMN1; SMN2 | |
| SCHEMBL7324031 | 0.83 | CASP1 (0.38) | CTSDCASP1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL7323405 | 0.80 | SYK (0.46) | CTSDCASP1MEN1KMT2A | |
| SCHEMBL9296296 | 0.80 | MEN1 (0.35) | CTSDCASP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7331042 | 0.80 | CASP1 (0.43) | CTSDCASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |