Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930610 | 0.95 | DPP7 (0.46) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL928991 | 0.93 | RRM1 (0.45) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL929992 | 0.89 | TDP1 (0.39) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL929089 | 0.85 | USP2 (0.43) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL929760 | 0.80 | ALDH1A1 (0.52) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL930855 | 0.80 | TDP1 (0.42) | DPP7ALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL931004 | 0.79 | USP2 (0.42) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL928482 | 0.78 | ALDH1A2 (0.44) | DPP7RRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL929789 | 0.75 | ALDH1A1 (0.50) | DPP7RRM1ALDH1A1LMNAMAPT | |
| SCHEMBL27611004 | 0.74 | ECE1 (0.37) | DPP7RRM1ALDH1A1HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875268-B2 | The use of certain dimercaptoamides as reducing agents, 2-mercapto-N-(2-mercaptoethyl)acetamide, results in curling that is satisfactoryin terms of intensity and in terms of hold over time; less substantial degradation of the hair fiber compared with the reducing agents of the prior art; permanent waves | L'OREAL S.A. (FR) | 2011-01-25 | — | — | US | claimed |
| EP-1584615-B1 | Use of dimercaptoamides for permanently deforming of keratinic fibres | OREAL (FR) | 2008-05-28 | — | — | EP | claimed |
| US-9476087-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-10-25 | — | — | US | disclosed |
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | UNIV NANYANG TECH (SG) | 2014-10-30 | — | — | US | disclosed |
| US-8802387-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-08-12 | — | — | US | disclosed |
| US-7875268-B2 | The use of certain dimercaptoamides as reducing agents, 2-mercapto-N-(2-mercaptoethyl)acetamide, results in curling that is satisfactoryin terms of intensity and in terms of hold over time; less substantial degradation of the hair fiber compared with the reducing agents of the prior art; permanent waves | L'OREAL S.A. (FR) | 2011-01-25 | — | — | US | disclosed |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | NANYANG TECHNOLOGICAL UNIVERSITY | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | DPP7 363/4885RRM1 1656/4885GNAI3 1579/4885 |
| US-20090275065-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | DPP7 358/4885RRM1 1566/4885GNAI3 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.