Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299750 | 0.88 | FFAR1 (0.43) | FFAR1CYP2A6ALOX5PTGESCHRNB2 | |
| SCHEMBL9298814 | 0.87 | ALOX5 (0.51) | FFAR1ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9192422 | 0.85 | FFAR1 (0.58) | FFAR1CYP2A6ALOX5PTGS1PTGS2 | |
| SCHEMBL9299666 | 0.81 | PTGES (0.44) | ALOX5PTGS1PTGS2PTGESAKR1C3 | |
| SCHEMBL9299859 | 0.80 | ACACB (0.42) | ALOX5PTGS1PTGS2PTGESAKR1C3 | |
| SCHEMBL9300204 | 0.79 | PTGES (0.46) | FFAR1ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9197649 | 0.78 | PTGES (0.59) | FFAR1CYP2A6ALOX5PTGS1PTGS2 | |
| SCHEMBL9299977 | 0.78 | ALOX5 (0.39) | FFAR1CYP2A6ALOX5PTGS1PTGS2 | |
| SCHEMBL9300560 | 0.78 | ALOX5 (0.44) | FFAR1ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9299028 | 0.76 | PTGES (0.45) | FFAR1CYP2A6ALOX5PTGESCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |