Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299499 | 0.89 | PTGES (0.42) | PTGESGRM5ALOX5PTPRCEPHX2 | |
| SCHEMBL9299859 | 0.86 | ACACB (0.42) | PTGESALOX5PTGS1PTGS2AKR1C3 | |
| SCHEMBL9298814 | 0.86 | ALOX5 (0.51) | PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL9300204 | 0.84 | PTGES (0.46) | PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL9299128 | 0.81 | FFAR1 (0.43) | PTGESGRM5ALOX5PTGS1PTGS2 | |
| SCHEMBL9299238 | 0.80 | ACACB (0.46) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9299806 | 0.79 | ALOX5 (0.41) | PTGESALOX5PTGS1PTGS2PTGDR2 | |
| SCHEMBL9300627 | 0.78 | ALOX5 (0.45) | PTGESALOX5PTGS1PTGS2 | |
| SCHEMBL9299977 | 0.77 | ALOX5 (0.39) | GRM5ALOX5PTGS1PTGS2 | |
| SCHEMBL9299975 | 0.75 | ACACB (0.43) | GRM5ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |