Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298814 | 0.83 | ALOX5 (0.51) | ALOX5PTGS1PTGS2FFAR1PTGES | |
| SCHEMBL9299806 | 0.79 | ALOX5 (0.41) | ALOX5PTGS1PTGS2ALDH1A1NPSR1 | |
| SCHEMBL9299128 | 0.78 | FFAR1 (0.43) | ALOX5PTGS1PTGS2FFAR1PTGES | |
| SCHEMBL9299975 | 0.77 | ACACB (0.43) | ALOX5PTGS1PTGS2GRM5 | |
| SCHEMBL9299899 | 0.76 | ALOX5 (0.39) | ALOX5PTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL9300599 | 0.76 | ALDH1A1 (0.43) | ALOX5ALDH1A1MAPTPKMHPGD | |
| SCHEMBL9299859 | 0.76 | ACACB (0.42) | ALOX5PTGS1PTGS2ALDH1A1HTT | |
| SCHEMBL9300204 | 0.75 | PTGES (0.46) | ALOX5PTGS1PTGS2ALDH1A1MAPT | |
| SCHEMBL9299666 | 0.74 | PTGES (0.44) | ALOX5PTGS1PTGS2PTGESAKR1C3 | |
| SCHEMBL9299977 | 0.74 | ALOX5 (0.39) | ALOX5PTGS1PTGS2FFAR1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |