Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 17/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299307 | 0.88 | ALOX5 (0.41) | ALOX5PTGES | |
| SCHEMBL9299727 | 0.86 | FFAR1 (0.38) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9298814 | 0.86 | ALOX5 (0.51) | ALOX5PTGS1PTGS2PTGESMEN1 | |
| SCHEMBL9299121 | 0.84 | ACACB (0.41) | ALOX5PTGS1PTGS2PTGESMEN1 | |
| SCHEMBL9192563 | 0.82 | PTGES (0.56) | ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9299666 | 0.78 | PTGES (0.44) | ALOX5PTGS1PTGS2PTGES | |
| SCHEMBL9300204 | 0.76 | PTGES (0.46) | ALOX5PTGS1PTGS2PTGESMEN1 | |
| SCHEMBL9299028 | 0.76 | PTGES (0.45) | ALOX5PTGES | |
| SCHEMBL9300259 | 0.75 | ACHE (0.39) | ALOX5PTGESMEN1KMT2A | |
| SCHEMBL9197154 | 0.75 | PTGES (0.50) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326902-A | Oxyalkyne compounds, pharmaceutical compositions containing them and processes for preparing such compounds and compositions | GRUENENTHAL GMBH (DE) | 1994-07-05 | — | — | US | disclosed |