Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422094 | 0.77 | CES2 (0.46) | CES2CES1MMP2CA1CA2 | |
| SCHEMBL28891033 | 0.77 | CES2 (0.46) | CES2CES1CA12MMP2CA1 | |
| SCHEMBL28414250 | 0.77 | LMNA (0.48) | CES2CES1CA12CA1GSK3B | |
| SCHEMBL95085 | 0.76 | L3MBTL1 (0.48) | CES2CES1CA12CA14CA1 | |
| SCHEMBL9301191 | 0.75 | MEN1 (0.43) | CES2CES1CA12MMP2CA14 | |
| SCHEMBL28243879 | 0.75 | PARP1 (0.50) | MMP2CA14CA1ALDH1A1LMNA | |
| SCHEMBL11052358 | 0.74 | CES2 (0.54) | CES2CES1CA12MMP2CA14 | |
| SCHEMBL9301199 | 0.74 | KMT2A (0.41) | CA12MMP2CA14OGG1ALDH1A1 | |
| SCHEMBL28409854 | 0.72 | MAPT (0.53) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL6343638 | 0.69 | MAPT (0.55) | CES2CES1OGG1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903318-B | Preparation method of alkenyl phosphonate compound | 西北民族大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-110903318-A | Preparation method of alkenyl phosphonate compound | 西北民族大学 | 2020-03-24 | — | — | CN | disclosed |
| US-5328958-A | Thermoplastic resins based on vinyl aromatic/vinyl phosphonic acid copolymers and amine-terminated polymers | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5310808-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5292817-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-03-08 | — | — | US | disclosed |
| EP-0130439-B1 | PROCESS FOR THE PREPARATION OF VINYLPHOSPHONIC ACID OR VINYLPYROPHONIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0068350-B1 | PROCESS FOR PREPARING DERIVATIVES OF VINYL PHOSPHONIC OR VINYL PYROPHOSPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-07 | — | — | EP | disclosed |
| US-4529559-A | Process for making derivatives of vinylphosphonic acid or vinylpyrophosphonic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-16 | — | — | US | disclosed |
| EP-0130439-A1 | Process for the preparation of vinylphosphonic acid or vinylpyrophonic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-01-09 | — | — | EP | disclosed |
| US-4486357-A | Process for making vinylphosphonic acid or vinylpyrophosphonic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |
| EP-0068350-A1 | Process for preparing derivatives of vinyl phosphonic or vinyl pyrophosphonic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-05 | — | — | EP | disclosed |