SCHEMBL9301191

SCHEMBL9301191

C=C(c1ccc(Br)cc1)P(=O)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
OGG1 O15527 1/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
GSK3B P49841 3/20 0.37
CA12 O43570 1/20 0.37
MMP2 P08253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28029982 0.82 RAB9A (0.42) MEN1KMT2AMAPTLMNAMAPK1
SCHEMBL28119898 0.81 MAPT (0.52) MEN1KMT2AMAPTLMNAMAPK1
SCHEMBL9300378 0.80 LMNA (0.47) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL28030369 0.77 LOXL2 (0.51) HDAC3MAOB
SCHEMBL9300129 0.75 CES2 (0.46) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL28030381 0.72 GFER (0.39) KMT2AMAPTLMNARAB9AALDH1A1
SCHEMBL9301199 0.72 KMT2A (0.41) MEN1KMT2AMAPTLMNARAB9A
SCHEMBL3575516 0.69 MAPT (0.45) MEN1KMT2AMAPTLMNAMAPK1
SCHEMBL9548021 0.67 GSK3B (0.50) MEN1KMT2AMAPTLMNAMAPK1
SCHEMBL24534844 0.67 OGG1 (0.48) MEN1KMT2AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5310808-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-05-10 US disclosed
US-5292817-A Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-03-08 US disclosed