Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289237 | 0.85 | ALDH1A1 (0.46) | KMT2AGAALMNANPC1RAB9A | |
| SCHEMBL17289013 | 0.83 | SMN1; SMN2 (0.43) | KMT2AGAALMNANPC1HTT | |
| SCHEMBL9714149 | 0.83 | POLB (0.45) | KMT2ALMNAPOLBMEN1NPSR1 | |
| SCHEMBL9300129 | 0.74 | CES2 (0.46) | KMT2AGAALMNANPC1RAB9A | |
| SCHEMBL16868487 | 0.72 | GAA (0.49) | KMT2AGAALMNAHPGDNPC1 | |
| SCHEMBL9301191 | 0.72 | MEN1 (0.43) | KMT2ALMNARAB9AHDAC3HDAC1 | |
| SCHEMBL5051393 | 0.70 | KMT2A (0.44) | KMT2AGAALMNAHDAC1PTPN2 | |
| SCHEMBL7629194 | 0.68 | CA2 (0.60) | KMT2AGAALMNAPOLBMEN1 | |
| SCHEMBL16904240 | 0.68 | NPC1 (0.55) | HPGDNPC1RAB9AHDAC3HDAC1 | |
| SCHEMBL3364776 | 0.67 | GAA (0.47) | KMT2AGAALMNAPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310808-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-05-10 | — | — | US | disclosed |
| US-5292817-A | Flame-retardant thermoplastic copolymers based on vinyl phosphonate derivatives grafted onto rubber | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-03-08 | — | — | US | disclosed |