Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301460 | 0.91 | CACNA1G (0.62) | KMT2AMEN1CACNA1GKCNH2ALDH1A1 | |
| SCHEMBL9301847 | 0.88 | CACNA1G (0.64) | KMT2ACACNA1GKCNH2 | |
| SCHEMBL9303300 | 0.86 | L3MBTL1 (0.70) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9193205 | 0.84 | L3MBTL1 (0.59) | KDM4EL3MBTL1KMT2AMEN1CACNA1G | |
| SCHEMBL9192429 | 0.83 | KCNH2 (0.64) | KDM4EL3MBTL1KMT2ACACNA1GKCNH2 | |
| SCHEMBL9301892 | 0.81 | KMT2A (0.67) | KDM4EL3MBTL1KMT2AMEN1CACNA1G | |
| SCHEMBL9302474 | 0.81 | L3MBTL1 (0.64) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9189672 | 0.80 | CACNA1G (0.60) | KMT2AMEN1CACNA1GKCNH2MAPT | |
| SCHEMBL10379764 | 0.79 | L3MBTL1 (0.62) | KDM4EL3MBTL1KMT2AMEN1CACNA1G | |
| SCHEMBL9302848 | 0.79 | L3MBTL1 (0.74) | KDM4EL3MBTL1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342839-A | Useful for therapy of oxygen deficiency diseases of the brain | BASF AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |