Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302534 | 0.84 | KCNH2 (0.49) | OPRM1SLC18A3DRD2KCNH2HRH3 | |
| SCHEMBL9301059 | 0.83 | ALDH1A1 (0.52) | OPRM1KCNH2HRH3L3MBTL1 | |
| SCHEMBL9301817 | 0.78 | FDPS (0.38) | — | |
| SCHEMBL5075884 | 0.78 | FDPS (0.45) | — | |
| SCHEMBL6670360 | 0.78 | FDPS (0.45) | — | |
| SCHEMBL9301498 | 0.73 | OPRD1 (0.46) | OPRM1HRH3 | |
| SCHEMBL9301764 | 0.73 | FDPS (0.44) | L3MBTL1SIGMAR1 | |
| SCHEMBL9301258 | 0.73 | FDPS (0.38) | — | |
| SCHEMBL9301070 | 0.72 | FDPS (0.37) | — | |
| SCHEMBL6221180 | 0.71 | SLC18A3 (0.48) | OPRM1SLC18A3DRD2KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5148279-A | — | — | None | — | — | JP | disclosed |
| US-5352437-A | Uses n-butane as propellant; excellent in cracking sound when applied to skin | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5350743-A | Treatment of osteoporosis | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1994-09-27 | — | — | US | disclosed |
| JP-H05148279-A | BISPHOSPHONIC ACID DERIVATIVE | KAKEN PHARMACEUT CO LTD | 1993-06-15 | — | — | JP | disclosed |
| EP-0498424-A1 | Bisphosphonic acid derivatives and bone resorption inhibitors containing them | Kaken Pharmaceutical Co., Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |