Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31646363 | 0.76 | ADORA2B (0.45) | GAAADORA2BLMNAPDE4AADORA2A | |
| SCHEMBL9300704 | 0.69 | LMNA (0.57) | ADORA2BLMNAADORA2AMAPT | |
| SCHEMBL9308527 | 0.65 | ADORA2B (0.45) | GAAADORA2BLMNAPDE4AADORA2A | |
| SCHEMBL10346501 | 0.64 | MAPK1 (0.57) | GAASMN1; SMN2ADORA2BLMNAPDE4A | |
| SCHEMBL10346304 | 0.62 | LMNA (0.56) | SMN1; SMN2ADORA2BLMNARXFP1PDE4A | |
| SCHEMBL9301475 | 0.60 | ATAD2 (0.46) | ADORA2BLMNAPDE4AADORA2APDE4B | |
| SCHEMBL25165800 | 0.60 | TRPA1 (0.48) | GAASMN1; SMN2ADORA2BLMNAPDE4A | |
| SCHEMBL15724891 | 0.59 | ADORA2B (0.66) | SMN1; SMN2ADORA2BLMNARXFP1ADORA2A | |
| SCHEMBL23718338 | 0.59 | PDE4A (0.44) | ADORA2BLMNARXFP1PDE4AADORA2A | |
| SCHEMBL28456121 | 0.59 | KMT2A (0.60) | SMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314890-A | Treatment of asthma | MALESCI ISTITUTO FARMACOBIOLOGICO S.P.A. (IT) | 1994-05-24 | — | — | US | disclosed |