Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | EDNRA | P25101 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.51 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094871 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL1576750 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL13230136 | 0.83 | PKM (0.60) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL19613863 | 0.83 | LMNA (0.69) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| Sulfathiazole SCHEMBL30130508 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| Sulfathiazole SCHEMBL94165 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL326633 | 0.82 | ALDH1A1 (0.71) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| SCHEMBL1095177 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| Sulfathiazole SCHEMBL18425505 | 0.81 | ALDH1A1 (0.97) | ALDH1A1LMNAKDM4ECYP2C9EDNRA | |
| Sulfathiazole SCHEMBL468436 | 0.81 | ALDH1A1 (0.97) | ALDH1A1LMNAKDM4ECYP2C9EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317956-A | Bis (hetero) aryl thioether oxadiazines as fungicidal compounds | 拜耳公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116057056-A | Azabicyclo-substituted heterocyclic compounds as fungicides | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115803317-A | Azabicyclo (thio) amides as fungicidal compounds | 拜耳作物科学股份公司 | 2023-03-14 | — | — | CN | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20140357655-A1 | SPIROINDOLINE DERIVATIVES AS GONADOTROPIN- RELEASING HORMONE RECEPTOR ANTAGONISTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-5360802-A | Antagonists of cholecystokinin and gastrin | MERCK SHARPE & DOHME LTD. | 1994-11-01 | — | — | US | disclosed |
| EP-0514133-A1 | Benzodiazepine derivatives, compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357655-A1 | SPIROINDOLINE DERIVATIVES AS GONADOTROPIN- RELEASING HORMONE RECEPTOR ANTAGONISTS | GNRHR, FSHR, NR5A1 | ALDH1A1 1719/4885LMNA 314/4885KDM4E 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.