Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.78 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300510 | 0.88 | P2RY14 (1.00) | P2RY14ALOX5MAOBLTB4RLTB4R2 | |
| SCHEMBL9301058 | 0.85 | P2RY14 (0.73) | P2RY14ALOX5MAOBLTB4RLTB4R2 | |
| SCHEMBL9300644 | 0.84 | P2RY14 (0.78) | P2RY14ALOX5MAOBLTB4RLTB4R2 | |
| SCHEMBL9301072 | 0.79 | P2RY14 (0.71) | P2RY14ALOX5MAOBLTB4RLTB4R2 | |
| SCHEMBL7342141 | 0.75 | NR4A2 (0.70) | MAOB | |
| SCHEMBL7337987 | 0.74 | NR4A2 (0.72) | MAOBMRGPRX4 | |
| SCHEMBL2933136 | 0.74 | P2RY14 (0.70) | P2RY14ALOX5LTB4RLTB4R2MRGPRX4 | |
| SCHEMBL2931677 | 0.72 | P2RY14 (0.60) | P2RY14ALOX5MAOBLTB4RLTB4R2 | |
| SCHEMBL6652096 | 0.72 | ALOX5 (0.63) | P2RY14ALOX5MAOBMRGPRX4 | |
| SCHEMBL5921632 | 0.71 | MRGPRX4 (0.76) | P2RY14ALOX5MAOBMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308852-A | Cardiovascular disorders | MERCK FROSST CANADA, INC. (CA) | 1994-05-03 | — | — | US | disclosed |
| EP-0579304-A1 | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1994-01-19 | — | — | EP | disclosed |