Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847732 | 0.90 | HTT (0.43) | HTTMAPTALDH1A1RORCKDM4E | |
| SCHEMBL9301681 | 0.89 | HTT (0.42) | HTTMAPTRORCLMNASMN1; SMN2 | |
| SCHEMBL9301682 | 0.88 | RORC (0.42) | HTTMAPTRORCLMNASMN1; SMN2 | |
| SCHEMBL9303809 | 0.87 | HTT (0.41) | HTTMAPTALDH1A1RORCLMNA | |
| SCHEMBL9301930 | 0.87 | HTT (0.45) | HTTMAPTALDH1A1HPGDALOX15 | |
| SCHEMBL9301471 | 0.85 | RORC (0.41) | HTTMAPTRORCLMNASMN1; SMN2 | |
| SCHEMBL9302442 | 0.85 | RORC (0.41) | HTTMAPTRORCLMNASMN1; SMN2 | |
| SCHEMBL9301590 | 0.84 | MAPT (0.45) | HTTMAPTALDH1A1RORCGPR174 | |
| SCHEMBL9301575 | 0.83 | RORC (0.39) | HTTMAPTRORCLMNASMN1; SMN2 | |
| SCHEMBL9303841 | 0.82 | HPGD (0.35) | HTTHPGDRORCGPR174OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300516-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-05 | — | — | US | disclosed |
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |