Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301471 | 0.93 | RORC (0.41) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9301682 | 0.91 | RORC (0.42) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9847732 | 0.90 | HTT (0.43) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9302442 | 0.88 | RORC (0.41) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9301581 | 0.87 | HTT (0.50) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9301681 | 0.87 | HTT (0.42) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9302252 | 0.87 | ACHE (0.42) | RORCOPRM1OPRD1OGFRL1TP53 | |
| SCHEMBL9301575 | 0.86 | RORC (0.39) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9847718 | 0.81 | CYP11B2 (0.35) | HTTRORCCYP11B1CYP11B2OPRM1 | |
| SCHEMBL9301590 | 0.79 | MAPT (0.45) | HTTRORCMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |