Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302904 | 0.89 | ALDH1A1 (0.45) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9302026 | 0.79 | DRD3 (0.44) | DRD3GAARAD52KDM4EALDH1A1 | |
| SCHEMBL9303411 | 0.72 | ALDH1A1 (0.41) | DRD3GAARAD52KDM4EALDH1A1 | |
| SCHEMBL9302347 | 0.70 | SMN1; SMN2 (0.35) | DRD3GAARAD52ALDH1A1MEN1 | |
| SCHEMBL9302640 | 0.70 | ALDH1A1 (0.46) | DRD3GAAKDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9302455 | 0.69 | ALDH1A1 (0.45) | DRD3GAAKDM4EALDH1A1MEN1 | |
| SCHEMBL6803657 | 0.67 | DRD3 (0.53) | DRD3GAARAD52KDM4EALDH1A1 | |
| SCHEMBL9824152 | 0.67 | DRD3 (0.50) | DRD3GAARAD52KDM4EALDH1A1 | |
| SCHEMBL9824932 | 0.65 | DRD3 (0.50) | DRD3GAARAD52KDM4EALDH1A1 | |
| SCHEMBL8150286 | 0.65 | ALDH1A1 (0.46) | DRD3GAAKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3170481-A | — | — | None | — | — | JP | disclosed |
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |
| JP-H03170481-A | SUBSTITUTED PYRIMIDOBENZIMIDAZOLE DERIVATIVE | F HOFFMANN LA ROCHE AG | 1991-07-24 | — | — | JP | disclosed |