Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301963 | 0.86 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDDRD3KMT2A | |
| SCHEMBL6796406 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDDRD3KMT2A | |
| SCHEMBL9302026 | 0.79 | DRD3 (0.44) | ALDH1A1KDM4EHPGDDRD3KMT2A | |
| SCHEMBL9302877 | 0.76 | GRM5 (0.39) | ALDH1A1KDM4EHPGDKMT2ALMNA | |
| SCHEMBL9302233 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6807024 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDDRD3KMT2A | |
| SCHEMBL9302209 | 0.72 | PIK3CD (0.35) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL6799416 | 0.72 | THRB (0.46) | ALDH1A1KMT2AMEN1LMNAPOLB | |
| SCHEMBL9301938 | 0.72 | DRD3 (0.43) | ALDH1A1KDM4EHPGDDRD3KMT2A | |
| SCHEMBL6800569 | 0.70 | MEN1 (0.47) | ALDH1A1KDM4EHPGDDRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283248-A | Bactericides, enzyme inhibitor of DNA-gyrase in bacteria | HOFFMANN-LA ROCHE INC. (US) | 1994-02-01 | — | — | US | disclosed |