Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302237 | 0.87 | F10 (0.49) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303221 | 0.83 | NPC1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303131 | 0.83 | SIRT2 (0.46) | NPC1RAB9AF10 | |
| SCHEMBL9303554 | 0.83 | NPC1 (0.46) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303445 | 0.82 | NPC1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303936 | 0.81 | PTGES (0.52) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL9303274 | 0.79 | PLAU (0.62) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9302799 | 0.79 | RXFP1 (0.50) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9302926 | 0.78 | RAB9A (0.50) | NPC1RAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL9303507 | 0.78 | KDM4E (0.47) | NPC1RAB9AKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352704-A | Antiviral agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0434432-B1 | Guanidinobenzene derivatives | BANYU PHARMA CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| EP-0434432-A1 | Guanidinobenzene derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |