Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 4/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TCF4 | P15884 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303510 | 0.83 | ALOX15 (0.53) | NAMPTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9302374 | 0.82 | CACNA1B (0.53) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9302410 | 0.77 | LMNA (0.56) | NAMPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9302429 | 0.74 | TP53 (0.45) | NAMPTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9302421 | 0.69 | ITGA1 (0.53) | ITGA1NAMPTTRIM24ALDH1A1MAPT | |
| SCHEMBL31681336 | 0.69 | POLB (0.69) | ITGA1POLBKDM1AMAOATCF4 | |
| SCHEMBL2941161 | 0.69 | CA12 (0.69) | ITGA1POLBTCF4CTNNB1MEN1 | |
| SCHEMBL11705518 | 0.69 | CA1 (0.71) | ITGA1POLBCA1CA2KMT2A | |
| SCHEMBL894613 | 0.69 | POLB (0.82) | ITGA1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL9304262 | 0.68 | ALDH1A1 (0.54) | NAMPTPOLBCA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |