Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302374 | 0.84 | CACNA1B (0.53) | LIMK2CYP19A1PKMALDH1A1PGR | |
| SCHEMBL9301975 | 0.83 | CYP19A1 (0.54) | CYP19A1CYP1A2CYP3A4CYP2C19NAMPT | |
| SCHEMBL9302425 | 0.83 | ITGA1 (0.58) | ALDH1A1NAMPTMAPTMEN1KMT2A | |
| SCHEMBL9302410 | 0.80 | LMNA (0.56) | ALOX15PKMALDH1A1TSHRCYP1A2 | |
| SCHEMBL9302429 | 0.78 | TP53 (0.45) | ALOX15CYP19A1PKMALDH1A1NAMPT | |
| SCHEMBL9304262 | 0.78 | ALDH1A1 (0.54) | CYP19A1ALDH1A1CYP1A2CYP3A4NAMPT | |
| SCHEMBL9303027 | 0.76 | CXCR4 (0.45) | ALDH1A1LMNATP53MAPTMEN1 | |
| SCHEMBL9305039 | 0.75 | CYP19A1 (0.67) | ALOX15LIMK2CYP19A1PKMALDH1A1 | |
| SCHEMBL3791521 | 0.74 | PGR (0.81) | ALOX15CYP19A1PKMALDH1A1TSHR | |
| SCHEMBL9302327 | 0.74 | POLB (0.56) | ALDH1A1NAMPTLMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |