Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303640 | 0.87 | KMT2A (0.36) | CYP19A1POLBLMNASMN1; SMN2HTT | |
| SCHEMBL9304354 | 0.85 | ALDH1A1 (0.43) | CYP19A1POLBSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8980658 | 0.83 | PKM (0.37) | MAOBALDH1A1PKM | |
| SCHEMBL9173152 | 0.82 | ALDH1A1 (0.39) | MAOBGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL9173014 | 0.81 | MAOB (0.35) | MAOBALPLCYP19A1MAPT | |
| SCHEMBL9809787 | 0.80 | MEN1 (0.35) | MAOBALPL | |
| SCHEMBL9164262 | 0.79 | MAOB (0.44) | MAOBCYP19A1GABRG2GABRB3GABRA5 | |
| SCHEMBL8573189 | 0.78 | MAOB (0.40) | MAOBALPLCYP19A1HTTUSP2 | |
| SCHEMBL9302379 | 0.76 | MAOB (0.36) | MAOBLMNASMN1; SMN2HTTUSP2 | |
| SCHEMBL9143963 | 0.76 | DRD3 (0.46) | MAOBCYP19A1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT, ANALGESIC, HYPOTENSIVE AGENT | PIERRE FABRE MEDICAMENT (FR) | 1994-05-03 | — | — | US | disclosed |