Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304584 | 0.96 | MAOB (0.37) | MAOBTSHRPKMKDM4EALDH1A1 | |
| SCHEMBL8980658 | 0.92 | PKM (0.37) | MAOBTSHRPKMALDH1A1ACHE | |
| SCHEMBL9809777 | 0.82 | MAOB (0.40) | MAOBKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL9809658 | 0.80 | CASP3 (0.36) | MAOBTSHRKDM4EALDH1A1ALOX15 | |
| SCHEMBL7386417 | 0.79 | ALDH1A1 (0.46) | TSHRKDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL8578943 | 0.77 | PRMT5 (0.39) | TSHRPKMKDM4EALDH1A1ALOX15 | |
| SCHEMBL13438368 | 0.77 | TSHR (0.39) | MAOBTSHRPKMKDM4EALOX15 | |
| SCHEMBL9303640 | 0.77 | KMT2A (0.36) | TSHRKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8577745 | 0.77 | KMT2A (0.48) | MAOBTSHRALDH1A1ALOX15MAPT | |
| SCHEMBL8980560 | 0.76 | PKM (0.36) | MAOBTSHRPKMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT, ANALGESIC, HYPOTENSIVE AGENT | PIERRE FABRE MEDICAMENT (FR) | 1994-05-03 | — | — | US | disclosed |