Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302635 | 0.87 | MAOB (0.36) | MAPTALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL9304354 | 0.86 | ALDH1A1 (0.43) | MAPTALDH1A1POLBTDP1SMN1; SMN2 | |
| SCHEMBL8980658 | 0.84 | PKM (0.37) | ALDH1A1TSHR | |
| SCHEMBL31562951 | 0.82 | KMT2A (0.38) | KMT2AMEN1CYP1A2CYP2C9MAPT | |
| SCHEMBL6436979 | 0.82 | ALDH1A1 (0.36) | KMT2AMEN1CYP1A2CYP2C9MAPT | |
| SCHEMBL9171003 | 0.81 | MEN1 (0.41) | KMT2AMEN1CYP1A2CYP2C9MAPT | |
| SCHEMBL9809787 | 0.81 | MEN1 (0.35) | KMT2AMEN1KDM4E | |
| SCHEMBL9174068 | 0.79 | MEN1 (0.43) | KMT2AMEN1CYP1A2CYP2C9MAPT | |
| SCHEMBL9174767 | 0.79 | KMT2A (0.43) | KMT2AMEN1CYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL9302379 | 0.77 | MAOB (0.36) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308844-A | ANTIDEPRESSANT, ANXIOLYTIC AGENT, ANALGESIC, HYPOTENSIVE AGENT | PIERRE FABRE MEDICAMENT (FR) | 1994-05-03 | — | — | US | disclosed |