SCHEMBL9302673

SCHEMBL9302673

Cc1ccc(CNC(=O)c2ccccc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.75
LMNA P02545 3/20 0.71
HDAC6 Q9UBN7 4/20 0.71
HDAC1 Q13547 4/20 0.71
POLB P06746 3/20 0.69
SMN1; SMN2 Q16637 1/20 0.69
ALDH1A1 P00352 3/20 0.67
MAPT P10636 2/20 0.67
KDM4E B2RXH2 2/20 0.67
HTT P42858 1/20 0.67
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
RECQL P46063 1/20 0.66
BLM P54132 1/20 0.66
MCL1 Q07820 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
HDAC3 O15379 2/20 0.65
HPGD P15428 1/20 0.62
HDAC2 Q92769 2/20 0.62
HDAC8 Q9BY41 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178366 0.93 MAPK14 (0.75) MAPK14LMNAHDAC6HDAC1POLB
SCHEMBL13932522 0.91 ALDH1A1 (0.78) MAPK14LMNAHDAC6HDAC1POLB
SCHEMBL1927145 0.90 EPHX2 (0.77) MAPK14LMNAHDAC6HDAC1POLB
SCHEMBL457082 0.87 HDAC6 (0.79) LMNAHDAC6HDAC1ALDH1A1HPGD
SCHEMBL31061058 0.86 MAPK14 (1.00) MAPK14LMNASMN1; SMN2ALDH1A1MAPT
SCHEMBL1927512 0.86 EPHX2 (0.77) MAPK14LMNAHDAC6HDAC1SMN1; SMN2
SCHEMBL19358924 0.86 MAPT (0.74) LMNAPOLBSMN1; SMN2ALDH1A1MAPT
SCHEMBL15985750 0.85 MAPK14 (0.65) MAPK14LMNAHDAC6HDAC1POLB
Hydrochloric Acid SCHEMBL3757721 0.85 HDAC6 (0.76) LMNAHDAC6HDAC1ALDH1A1HPGD
SCHEMBL29184442 0.85 HDAC6 (0.76) LMNAHDAC6HDAC1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115505278-B Recycled plant composite fiber and preparation method thereof 陆进貌 2024-09-27 CN claimed
CN-118390297-A Preparation method of recycled plant composite fiber 陆进貌 2024-07-26 CN claimed
CN-108884021-A Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof 启明大学校产学协力团 2018-11-23 CN claimed
CN-115505278-B Recycled plant composite fiber and preparation method thereof 陆进貌 2024-09-27 CN disclosed
CN-115505278-B Recycled plant composite fiber and preparation method thereof 陆进貌 2024-09-27 CN disclosed
CN-118390297-A Preparation method of recycled plant composite fiber 陆进貌 2024-07-26 CN disclosed
CN-118390297-A Preparation method of recycled plant composite fiber 陆进貌 2024-07-26 CN disclosed
CN-117243839-A Minoxidil adjuvant therapy 应用生物学股份有限公司 2023-12-19 CN disclosed
CN-115505278-A Recycled plant composite fiber and preparation method thereof 陆进貌 2022-12-23 CN disclosed
CN-115505278-A Recycled plant composite fiber and preparation method thereof 陆进貌 2022-12-23 CN disclosed
CN-108884021-A Novel compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof and medical use thereof 启明大学校产学协力团 2018-11-23 CN disclosed
US-20140120087-A1 TRIAZOLOPYRIDINES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-05-01 US disclosed
CN-103113176-A Method for synthesizing N-alkenamide UNIV NANJING SCIENCE & TECH 2013-05-22 CN disclosed
EP-1523473-B1 INDOLINE DERIVATIVES SUBSTITUTED IN POSITION 6, PRODUCTION AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA (DE) 2013-02-27 EP disclosed
US-8093227-B2 Monosaccharide compounds and methods therefor ALCHEMIA PTY LTD (AU) 2012-01-10 US disclosed
US-20100184607-A1 MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR ALCHEMIA PTY LTD. (AU) 2010-07-22 US disclosed
US-7417129-B2 Combinatorial libraries of monosaccharides ALCHEMIA PTY LTD (AU) 2008-08-26 US disclosed
US-5314880-A Platelet activating factor antagonist BRITISH BIO-TECHNOLOGY LIMITED (GB) 1994-05-24 US disclosed
EP-0468971-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1992-02-05 EP disclosed
WO-1990009997-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1990-09-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140120087-A1 TRIAZOLOPYRIDINES QDPR, TBXA2R, KCNJ11 MAPK14 4701/4885LMNA 1537/4885HDAC6 2900/4885
US-20100184607-A1 MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR SLC5A1, UGGT1, MRPL21 MAPK14 567/4885LMNA 4069/4885HDAC6 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.